Cannon Group
Carolyn L. Cannon, M.D., Ph.D.
Acute Lung Injury
Co-Investigator
Associate Professor of Pediatrics
Division of Respiratory Medicine
University of Texas - Southwestern Medical Center at Dallas
Dallas, TX
Goals for the Initial PEN grant
Carolyn L. Cannon was involved in the Acute Lung Injury project.
Facilities
The Cannon group has access to the state-of-the-art Animal Resources Center (ARC) at the University of Texas Southwestern Medical Center, which is managed and staffed by veterinarians and professional animal care personnel. The ARC houses animals is a building immediately adjacent to the 600 sq. ft. of laboratory space in the Division of Pulmonary and Vascular Biology of the Department of Pediatrics of which the Cannon group has exclusive use. The laboratory space includes two fume hoods to allow housing of infected animals in the laboratory and treatment with nebulized antimicrobial-loaded nanoparticles. Balances, microcentrifuges, homogenizers, waterbaths, protein electrophoresis and immunoblot equipment, standard thermal cyclers, Northern and Southern analysis equipment, 3 laminar flow hoods and 6 cell culture incubators, a spectrophotometer, a shaking floor incubator, a Speed-Vac, two phase-contrast microscope, a tabletop ultracentrifuge, two liquid nitrogen storage dewars, a luminometer, an ABI Prism 7700 Sequence Detection System, three
-70°C freezers, refrigerators, and -20°C freezers are located either in the Cannon laboratory or in neighboring laboratories. A lowspeed centrifuge, a sonicator, a Beckman L7-65 ultracentrifuge, a gamma spectrometer (Packard Model 5382), and a liquid scintillation spectrometer (Packard Model 3255) are located in other Department of Pediatrics laboratories nearby. On the same floor as the laboratory space, there is a 200 sq. ft. room for small animal surgery, which has dissecting microscopes and other small animal surgery equipment for the infection and harvest procedures. This room and equipment are shared amongst nearby investigators in the Department of Pediatrics. The Cannon group has access to another nearby 200 sq. ft. room devoted exclusively to cell culture that is shared with three other investigators. A cold room and a darkroom are a few doors down the hall.
People
Carolyn L. Cannon, M.D., Ph.D.
Co-Investigator
Associate Professor of Pediatrics
Division of Respiratory Medicine
University of Texas - Southwestern Medical Center
Dallas, TX
phone: (214) 648-8709
carolyn.cannon@utsouthwestern.edu
Parth Shah
Postdoctoral Researcher II
University of Texas - Southwestern Medical Center
Dallas, TX
phone: (214) 648-8709
Parth.Shah@UTSouthwestern.edu