Cannon Group
Carolyn L. Cannon, M.D., Ph.D.
Project 2 - Nanomaterials for treatment of infectious lung diseases
Co-Investigator
Department of Pediatrics
Divisions of Respiratory Medicine and Pulmonary and Vascular Biology
Associate Director, Division of Respiratory Medicine
Director, Pediatric Pulmonology Fellowship Program
University of Texas Southwestern Medical Center
Goals for the Current PEN Contract
Carolyn L. Cannon is the project leader for Project 2.
Facilities
The Cannon group has access to the state-of-the-art Animal Resources Center (ARC) at the University of Texas Southwestern Medical Center, which is managed and staffed by veterinarians and professional animal care personnel. The ARC houses animals is a building immediately adjacent to the 600 sq. ft. of laboratory space in the Division of Pulmonary and Vascular Biology of the Department of Pediatrics of which the Cannon group has exclusive use. The laboratory space includes two fume hoods to allow housing of infected animals in the laboratory and treatment with nebulized antimicrobial-loaded nanoparticles. Balances, microcentrifuges, homogenizers, waterbaths, protein electrophoresis and immunoblot equipment, standard thermal cyclers, Northern and Southern analysis equipment, 3 laminar flow hoods and 6 cell culture incubators, a spectrophotometer, a shaking floor incubator, a Speed-Vac, two phase-contrast microscope, a tabletop ultracentrifuge, two liquid nitrogen storage dewars, a luminometer, an ABI Prism 7700 Sequence Detection System, three
-70°C freezers, refrigerators, and -20°C freezers are located either in the Cannon laboratory or in neighboring laboratories. A lowspeed centrifuge, a sonicator, a Beckman L7-65 ultracentrifuge, a gamma spectrometer (Packard Model 5382), and a liquid scintillation spectrometer (Packard Model 3255) are located in other Department of Pediatrics laboratories nearby. On the same floor as the laboratory space, there is a 200 sq. ft. room for small animal surgery, which has dissecting microscopes and other small animal surgery equipment for the infection and harvest procedures. This room and equipment are shared amongst nearby investigators in the Department of Pediatrics. The Cannon group has access to another nearby 200 sq. ft. room devoted exclusively to cell culture that is shared with three other investigators. A cold room and a darkroom are a few doors down the hall.
People
Carolyn L. Cannon, M.D., Ph.D.
Co-Investigator
Department of Pediatrics
Divisions of Respiratory Medicine and Pulmonary and Vascular Biology
Associate Director, Division of Respiratory Medicine
Director, Pediatric Pulmonology Fellowship Program
University of Texas Southwestern Medical Center
5323 Harry Hines Blvd
Dallas, TX 75390-9063
phone: (214) 648-8709
fax: (214) 648-2096
carolyn.cannon@utsouthwestern.edu
Parth Shah, Ph.D.
Postdoctoral Researcher
University of Texas Southwestern Medical Center
5323 Harry Hines Blvd
Dallas, TX 75390-9063
phone: (214) 648-9286
parth.shah@UTSouthwestern.edu
Justin Smolen, M.S.
Research Associate, Laboratory Manager
University of Texas Southwestern Medical Center
5323 Harry Hines Blvd
Dallas, TX 75390-9063
phone: (214) 648-9587
justin.smolen@utsouthwestern.edu
Kangmee Woo, Ph.D.
Research Scientist
University of Texas Southwestern Medical Center
5323 Harry Hines Blvd
Dallas, TX 75390-9063
phone: (214) 648-9286
kangmee.woo@utsouthwestern.edu
(Minna) Ae Gyeong Kang, M.S.
Staff Associate
University of Texas Southwestern Medical Center
5323 Harry Hines Blvd
Dallas, TX 75390-9063
phone: (214) 648-9286
ae.kang@utsouthwestern.edu